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Cytotoxic effect of compounds 5a-5e <t>on</t> <t>MCF-7</t> cells following exposure to different concentrations (10, 20, 60, and 100 μM). Data are presented as mean ± SD, n = 3. *P < 0.05, **P < 0.01, and *** P < 0.001 indicate significant differences in comparison with the negative control group (untreated cells); doxorubicin was used as the positive control.
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Cytotoxic effect of compounds 5a-5e on MCF-7 cells following exposure to different concentrations (10, 20, 60, and 100 μM). Data are presented as mean ± SD, n = 3. *P < 0.05, **P < 0.01, and *** P < 0.001 indicate significant differences in comparison with the negative control group (untreated cells); doxorubicin was used as the positive control.

Journal: Research in Pharmaceutical Sciences

Article Title: Molecular docking, synthesis, and cytotoxic evaluation of novel quinazoline-quinazolinone hybrid compounds

doi: 10.4103/RPS.RPS_150_24

Figure Lengend Snippet: Cytotoxic effect of compounds 5a-5e on MCF-7 cells following exposure to different concentrations (10, 20, 60, and 100 μM). Data are presented as mean ± SD, n = 3. *P < 0.05, **P < 0.01, and *** P < 0.001 indicate significant differences in comparison with the negative control group (untreated cells); doxorubicin was used as the positive control.

Article Snippet: The MCF-7 (human breast cancer) cell line was acquired from the Pasteur Institute of Iran (Tehran, Iran).

Techniques: Comparison, Negative Control, Positive Control